An article in JAMA Psychiatry advises very slow tapering for best results when discontinuing antipsychotic drugs. The article was written by prominent UK researchers Mark Horowitz, Robin Murray, and David Taylor.
Horowitz, Murray, and Taylor write,
“As there is some evidence that not all patients need lifelong antipsychotic treatment and some may have improved social functioning when taking less or no antipsychotic, cautious deprescribing should be a component of high-quality prescribing practice.”